Clinical utility of urinary antigen test and molecular method for detection of Legionella pneumophila.

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Laboratory Diagnosis of Pneumonia by Detection of Urinary Antigen Test of Legionella Pnuemophilia

Background and Aims: Legionnaires’ disease is seen in sporadic and epidemic form. The most prevalent cause is Legionella pnuemophilia (L.pneumophila), which produces a severe disease in vulnerable individuals with a high fatality rate. This study was conducted due to the wide and universal distribution of the Legionnaires’ disease, lack of conventional and accessible diagnostic meth...

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urinary antigen test eia: a valuable rapid clinical method for the ddiagnosis of legionella

background community acquired pneumonia (cap) is a common health concern and the main mortality factor worldwide. nowadays, legionella pneumophila is one of the most common microorganisms responsible for cap. we designed this study to investigate the antigen test as a useful, simple and rapid test for early diagnosis of legionella pneumophila. materials and methods we enrolled 118 patients (32 ...

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molecular detection of legionella pneumophila within culture-negative samples

introduction: l. pneumophila is the most important cause of legionaires, disease, which is currently reported either as a nosocomial or community acquired infection. rapid and reliable diagnosis of legionella has hampered the epidemiological studies and disease control activities. in spite of good sensitivity and specificity, the culture method encountered serious shortcomings. polymerase chain...

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Centrifugal ultrafiltration method for rapid concentration of Legionella pneumophila urinary antigen.

Detection of Legionella pneumophila antigen in urine by enzyme immunoassay (EIA) or by immunochromatographic testing (ICT) has proven rapid, sensitive, and specific for diagnosing legionellosis (2, 3, 5, 6). Although it requires added processing time, the use of concentrated urine (CU) obtained by selective ultrafiltration significantly improves the sensitivity (1) of antigen detection. We asse...

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Evaluation of the Oxoid Xpect Legionella test kit for detection of Legionella pneumophila serogroup 1 antigen in urine.

We evaluated a new immunochromatographic assay (Oxoid Xpect Legionella test kit) for the ability to detect Legionella pneumophila serogroup 1 antigen in urine. The results were compared with those obtained with the Binax NOW urinary antigen test by following the manufacturers' instructions. The sensitivities and specificities were estimated to be 89 and 100%, respectively, for the Oxoid Xpect L...

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ژورنال

عنوان ژورنال: International Journal of Research in Pharmaceutical Sciences

سال: 2018

ISSN: 0975-7538

DOI: 10.26452/ijrps.v9ispl1.1311